Research interests:
Developmental biology, Systems biology and Mathematical modeling
Research interests :
Current Research projects:
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Developing the approach for generic mathematical formalization of the phenomena of pattern
formation in morphogenesis (math-bio group in IHES).
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Network modeling of proliferation / cancer / apoptotic pathways in human lung cancer cells
using a genome-wide loss-of-function screen (with PARi platform).
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Systems biology approach for genome-wide loss-of-function screen analysis, with applications
related to lung cancer research (with PARi platform).
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Biostatistics for genome-wide screen analysis (with PARi platform).
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Mathematical modeling of the different mechanisms of microRNA action with the final aim to get
dynamical signatures for each proposed mechanism (with Dr. Zinovyev, Institut Curie).
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Bioinformatic analysis of the deep sequencing of small non-coding RNAs associated with
chromatin AGO-complexes.
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microRNA profiling for the processes of proliferation, differentiation and cancerogenesis using
LNA microarray and TLDA qPCR technique.
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Mathematical modeling of cancer stem-like cell population dynamics
(with Prof. Capasso, University of Milano).
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Mathematical modeling of the processes of plant growth (with Dr. V. Volpert, Lyon).
Scientific Collaborations:
Dr. A. Zinovyev, Institut Curie, France
Prof. V. Capasso, University of Milan, Italy
Dr. V. Volpert, University of Lyon, France
Prof. M. Gromov, IHES, France