Nadya
Morozova
FRE CNRS 3377 "Epigenetique et
cancer"
CEA Saclay
91191 Gif-sur-Yvette France
Tel: 01 69 08 53 15
Fax: 01 69 08 53 48
CEA Saclay
91191 Gif-sur-Yvette France
Tel: 01 69 08 53 15
Fax: 01 69 08 53 48
e-mail:
Education
: M.S in Molecular
Biology and
M.S in Theoretical Physics and
Ph.D in Developmental Biology
Developmental biology, Systems biology and Mathematical modeling
Research interests :
• Cancer biology, with a
particular focus on lung and breast cancer
• Stem cells and Cancer Stem-like cells populations
• Small non-coding RNAs
• Cell fate determination in the processes of proliferation and differentiation
• Pathway and Network analysis
• Mathematical modeling of the processes of growth and development
• Mathematical formalization of pattern formation in morphogenesis
• Data processing tools for small-scale and genome-wide screens
• Stem cells and Cancer Stem-like cells populations
• Small non-coding RNAs
• Cell fate determination in the processes of proliferation and differentiation
• Pathway and Network analysis
• Mathematical modeling of the processes of growth and development
• Mathematical formalization of pattern formation in morphogenesis
• Data processing tools for small-scale and genome-wide screens
Current Research projects:
•
Network modeling of
proliferation/cancer/apoptotic pathways in human lung cancer cells
using a genome-wide loss of function screen.(with PARi platform)
• Systems biology approach for genome-wide loss-of-function screen analysis, with applications related to lung cancer research.(with PARi platform)
• Biostatistics for genome-wide screen analysis ( with PARi platform)
• Mathematical modeling of the different mechanisms of microRNA action with the final aim to get dynamical signatures for each proposed mechanism.(with Dr. Zinovyev, Institute Curie)
• Bioinformatic analysis of the deep sequencing of small non-coding RNAs, associated with chromatin AGO-complexis.
• microRNA profiling for the processes of proliferation, differentiation and cancerogenesis using LNA microarray and TLDA qPCR technique.
• Mathematical modeling of cancer stem-like cells population dynamics(with Prof. Capasso, University of Milano)
• Mathematical modeling of the processes of plant growth (with Dr. V. Volpert, Lyon)
• Developing the approach for generic mathematical formalization of the phenomena of Pattern formation in Morphogenesis. (math-bio group in IHES)
• Systems biology approach for genome-wide loss-of-function screen analysis, with applications related to lung cancer research.(with PARi platform)
• Biostatistics for genome-wide screen analysis ( with PARi platform)
• Mathematical modeling of the different mechanisms of microRNA action with the final aim to get dynamical signatures for each proposed mechanism.(with Dr. Zinovyev, Institute Curie)
• Bioinformatic analysis of the deep sequencing of small non-coding RNAs, associated with chromatin AGO-complexis.
• microRNA profiling for the processes of proliferation, differentiation and cancerogenesis using LNA microarray and TLDA qPCR technique.
• Mathematical modeling of cancer stem-like cells population dynamics(with Prof. Capasso, University of Milano)
• Mathematical modeling of the processes of plant growth (with Dr. V. Volpert, Lyon)
• Developing the approach for generic mathematical formalization of the phenomena of Pattern formation in Morphogenesis. (math-bio group in IHES)
Scientific Collaborations:
Dr. A. Zinovyev, Institute Curie,
France
Prof. V. Capasso, University of Milan, Italy
Dr. V.Volpert, University of Lyon, France
Prof. M. Shubin, NEU, USA
Prof. M. Gromov, IHES, France
Prof. V. Capasso, University of Milan, Italy
Dr. V.Volpert, University of Lyon, France
Prof. M. Shubin, NEU, USA
Prof. M. Gromov, IHES, France
• Scientific
International
Projects (on-going and finalized)