Our laboratory is working on various problems connected with the functioning and evolution of biological systems. In particular, we are interested in the systemic description of genetic and biochemical networks, such as those responsible for gene regulation. Our approach is based on quantitative experimental measurements and theoretical modeling. We use mathematical tools (mainly from statistics and combinatorics) and algorithmic tools to study basic principles of cellular functioning starting from genomic data.

Equipe de Génomique Analytique
Laboratoire de Immuno-biologie Cellulaire et Moléculaire des Infections Parasitaires, INSERM U511
Faculté de Médicine, Université Pierre et Marie Curie
91, bd de l'Hôpital
75013 Paris, FRANCE
Tel. lab: +33 (0)1.40.77.81.03
Tel. secretary : +33 (0)1.40.77.97.36
Fax. +33 (0)1.45.83.88.58
How to come: plan

• comparative genomics (codon bias, gene expression levels, metabolic networks)
• statistical and combinatorial analysis of Plasmodium genomes
• genetic network of Plasmodium Falciparum
• low homology and protein annotation
• protein-protein and protein-DNA interaction
  

• DNA nanotechnologies
• DNA tiling