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1: GO: Molecular Function [Display Chart] 231 annotations before applied cutoff / 18819 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0004812 aminoacyl-tRNA ligase activity 1.898E-5 1.461E-3 8.800E-3 4.384E-3 4 44
2 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds 1.898E-5 1.461E-3 8.800E-3 4.384E-3 4 44
3 GO:0016875 ligase activity, forming carbon-oxygen bonds 1.898E-5 1.461E-3 8.800E-3 4.384E-3 4 44
4 GO:0042300 beta-amyrin synthase activity 3.552E-4 1.026E-2
6.176E-2
8.205E-2
 2 8
5 GO:0042299 lupeol synthase activity 3.552E-4 1.026E-2
6.176E-2
8.205E-2
 2 8
6 GO:0080011 baruol synthase activity 3.552E-4 1.026E-2
6.176E-2
8.205E-2
 2 8
7 GO:0034784 pivalyl-CoA mutase activity 3.552E-4 1.026E-2
6.176E-2
8.205E-2
 2 8
8 GO:0034951 o-hydroxylaminobenzoate mutase activity 3.552E-4 1.026E-2
6.176E-2
8.205E-2
 2 8
9 GO:0031559 oxidosqualene cyclase activity 4.556E-4 1.120E-2
6.745E-2
1.052E-1
 2 9
10 GO:0003729 mRNA binding 4.849E-4 1.120E-2
6.745E-2
1.120E-1
 5 180
11 GO:0003697 single-stranded DNA binding 5.664E-4 1.190E-2
7.163E-2
1.308E-1
 4 105
12 GO:0000049 tRNA binding 7.381E-4 1.421E-2
8.556E-2
1.705E-1
 3 49
13 GO:0009982 pseudouridine synthase activity 9.780E-4 1.738E-2
1.046E-1
2.259E-1
 2 13
14 GO:0005487 nucleocytoplasmic transporter activity 3.373E-3 4.928E-2
2.967E-1
7.792E-1
 2 24
15 GO:0050561 glutamate-tRNA(Gln) ligase activity 3.626E-3 4.928E-2
2.967E-1
8.377E-1
 1 1
16 GO:0004730 pseudouridylate synthase activity 3.626E-3 4.928E-2
2.967E-1
8.377E-1
 1 1
17 GO:0050560 aspartate-tRNA(Asn) ligase activity 3.626E-3 4.928E-2
2.967E-1
8.377E-1
 1 1
Show 12 more annotations

2: GO: Biological Process [Display Chart] 1431 annotations before applied cutoff / 18785 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0006412 translation 7.585E-8 9.157E-5 7.183E-4 1.085E-4 14 667
2 GO:0043043 peptide biosynthetic process 1.280E-7 9.157E-5 7.183E-4 1.831E-4 14 696
3 GO:0043604 amide biosynthetic process 5.097E-7 2.230E-4 1.749E-3 7.293E-4 14 780
4 GO:0034660 ncRNA metabolic process 6.234E-7 2.230E-4 1.749E-3 8.921E-4 12 563
5 GO:0006402 mRNA catabolic process 1.048E-6 3.000E-4 2.353E-3 1.500E-3 8 218
6 GO:0006518 peptide metabolic process 1.378E-6 3.287E-4 2.579E-3 1.972E-3 14 848
7 GO:0006401 RNA catabolic process 2.665E-6 5.448E-4 4.273E-3 3.814E-3 8 247
8 GO:0006399 tRNA metabolic process 3.535E-6 6.323E-4 4.960E-3 5.059E-3 7 180
9 GO:0019080 viral gene expression 4.548E-6 7.231E-4 5.672E-3 6.508E-3 7 187
10 GO:0010608 posttranscriptional regulation of gene expression 7.008E-6 9.001E-4 7.060E-3 1.003E-2 10 478
11 GO:0044265 cellular macromolecule catabolic process 7.226E-6 9.001E-4 7.060E-3 1.034E-2 14 978
12 GO:0000956 nuclear-transcribed mRNA catabolic process 7.548E-6 9.001E-4 7.060E-3 1.080E-2 7 202
13 GO:0044033 multi-organism metabolic process 8.855E-6 9.748E-4 7.646E-3 1.267E-2 7 207
14 GO:0006418 tRNA aminoacylation for protein translation 2.775E-5 2.836E-3 2.225E-2 3.971E-2 4 49
15 GO:0043039 tRNA aminoacylation 3.517E-5 3.250E-3 2.549E-2
5.033E-2
 4 52
16 GO:0043038 amino acid activation 3.794E-5 3.250E-3 2.549E-2
5.430E-2
 4 53
17 GO:0019083 viral transcription 3.861E-5 3.250E-3 2.549E-2
5.525E-2
 6 176
18 GO:0006413 translational initiation 6.640E-5 5.279E-3 4.140E-2
9.502E-2
 6 194
19 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay 7.163E-5 5.395E-3 4.232E-2
1.025E-1
 5 121
20 GO:0006396 RNA processing 8.274E-5 5.920E-3 4.644E-2
1.184E-1
 12 914
21 GO:0016071 mRNA metabolic process 1.159E-4 7.298E-3
5.724E-2
1.658E-1
 10 665
22 GO:0034655 nucleobase-containing compound catabolic process 1.163E-4 7.298E-3
5.724E-2
1.665E-1
 8 418
23 GO:0022411 cellular component disassembly 1.173E-4 7.298E-3
5.724E-2
1.678E-1
 10 666
24 GO:0070127 tRNA aminoacylation for mitochondrial protein translation 1.245E-4 7.421E-3
5.820E-2
1.781E-1
 2 5
25 GO:0043488 regulation of mRNA stability 1.627E-4 9.315E-3
7.306E-2
2.329E-1
 5 144
26 GO:0019058 viral life cycle 1.842E-4 9.856E-3
7.731E-2
2.636E-1
 8 447
27 GO:0043487 regulation of RNA stability 1.908E-4 9.856E-3
7.731E-2
2.731E-1
 5 149
28 GO:0006409 tRNA export from nucleus 1.997E-4 9.856E-3
7.731E-2
2.858E-1
 3 32
29 GO:0071431 tRNA-containing ribonucleoprotein complex export from nucleus 1.997E-4 9.856E-3
7.731E-2
2.858E-1
 3 32
30 GO:0000959 mitochondrial RNA metabolic process 2.192E-4 1.012E-2
7.934E-2
3.136E-1
 3 33
31 GO:0044270 cellular nitrogen compound catabolic process 2.304E-4 1.012E-2
7.934E-2
3.298E-1
 8 462
32 GO:0046700 heterocycle catabolic process 2.373E-4 1.012E-2
7.934E-2
3.395E-1
 8 464
33 GO:0051031 tRNA transport 2.398E-4 1.012E-2
7.934E-2
3.431E-1
 3 34
34 GO:0006417 regulation of translation 2.403E-4 1.012E-2
7.934E-2
3.439E-1
 7 349
35 GO:0019439 aromatic compound catabolic process 2.740E-4 1.120E-2
8.786E-2
3.921E-1
 8 474
36 GO:0006614 SRP-dependent cotranslational protein targeting to membrane 3.541E-4 1.408E-2
1.104E-1
5.067E-1
 4 94
37 GO:0034248 regulation of cellular amide metabolic process 4.147E-4 1.580E-2
1.239E-1
5.934E-1
 7 382
38 GO:0019985 translesion synthesis 4.196E-4 1.580E-2
1.239E-1
6.004E-1
 3 41
39 GO:1901361 organic cyclic compound catabolic process 4.467E-4 1.639E-2
1.286E-1
6.392E-1
 8 510
40 GO:0006613 cotranslational protein targeting to membrane 4.653E-4 1.665E-2
1.306E-1
6.659E-1
 4 101
41 GO:0032480 negative regulation of type I interferon production 4.833E-4 1.687E-2
1.323E-1
6.915E-1
 3 43
42 GO:0045047 protein targeting to ER 5.012E-4 1.708E-2
1.339E-1
7.172E-1
 4 103
43 GO:0034470 ncRNA processing 5.376E-4 1.789E-2
1.403E-1
7.693E-1
 7 399
44 GO:0072599 establishment of protein localization to endoplasmic reticulum 5.788E-4 1.882E-2
1.477E-1
8.283E-1
 4 107
45 GO:0016236 macroautophagy 7.589E-4 2.413E-2
1.893E-1
1.000E0
 7 423
46 GO:0071426 ribonucleoprotein complex export from nucleus 8.900E-4 2.710E-2
2.125E-1
1.000E0
 4 120
47 GO:0006405 RNA export from nucleus 8.900E-4 2.710E-2
2.125E-1
1.000E0
 4 120
48 GO:0006301 postreplication repair 9.445E-4 2.816E-2
2.209E-1
1.000E0
 3 54
49 GO:0071166 ribonucleoprotein complex localization 9.757E-4 2.850E-2
2.235E-1
1.000E0
 4 123
50 GO:0006403 RNA localization 9.968E-4 2.853E-2
2.238E-1
1.000E0
 5 214
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 219 annotations before applied cutoff / 19172 genes in category

No results to display

4: Human Phenotype [Display Chart] 8 annotations before applied cutoff / 1813 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0001993 Ketoacidosis 5.516E-3 1.986E-2
5.397E-2
 4.413E-2 1 10
2 HP:0003074 Hyperglycemia 7.170E-3 1.986E-2
5.397E-2
5.736E-2
 1 13
3 HP:0001959 Polydipsia 8.825E-3 1.986E-2
5.397E-2
7.060E-2
 1 16
4 HP:0000103 Polyuria 9.928E-3 1.986E-2
5.397E-2
7.943E-2
 1 18
5 HP:0002591 Polyphagia 1.434E-2 2.295E-2
6.236E-2
1.147E-1
 1 26
6 HP:0002715 Abnormality of the immune system 1.931E-2 2.574E-2
6.996E-2
1.544E-1
 1 35
7 HP:0000819 Diabetes mellitus 3.254E-2 3.719E-2
1.011E-1
2.603E-1
 1 59
Show 2 more annotations

5: Mouse Phenotype [Display Chart] 762 annotations before applied cutoff / 9208 genes in category

No results to display

6: Domain [Display Chart] 432 annotations before applied cutoff / 16924 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR020103 PsdUridine synth cat dom InterPro 1.069E-3 2.827E-2
1.879E-1
4.618E-1
 2 13
2 IPR006195 Aminoacyl-tRNA-synth II InterPro 2.071E-3 2.827E-2
1.879E-1
8.949E-1
 2 18
3 IPR001412 aa-tRNA-synth I CS InterPro 2.071E-3 2.827E-2
1.879E-1
8.949E-1
 2 18
4 PS50862 AA TRNA LIGASE II PROSITE 2.071E-3 2.827E-2
1.879E-1
8.949E-1
 2 18
5 PS00178 AA TRNA LIGASE I PROSITE 2.310E-3 2.827E-2
1.879E-1
9.977E-1
 2 19
6 PF05739 SNARE Pfam 2.822E-3 2.827E-2
1.879E-1
1.000E0
 2 21
7 IPR013089 Kelch-related InterPro 2.979E-3 2.827E-2
1.879E-1
1.000E0
 3 76
8 SM00397 t SNARE SMART 3.097E-3 2.827E-2
1.879E-1
1.000E0
 2 22
9 IPR005485 Ribosomal L5 euk InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
10 PF01777 Ribosomal L27e Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
11 IPR019192 Ribosomal L28 mit InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
12 IPR023184 Ubol cytC Rdtase hinge dom InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
13 PS50935 SSB PROSITE 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
14 IPR018153 Asp-tRNA-synth IIb C bac/mt InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
15 PF09606 ARC105 Med act Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
16 G3DSA:1.10.287.20 Ubol cytC Rdtase hinge dom Gene3D 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
17 G3DSA:3.30.1360.30 GAD dom Gene3D 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
18 IPR018262 Ribosomal L27e CS InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
19 IPR008925 aa-tRNA-synth I codon-bd InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
20 PF03152 UFD1 Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
21 IPR000424 Primosome PriB/ssb InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
22 PS01107 RIBOSOMAL L27E PROSITE 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
23 PF01020 Ribosomal L40e Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
24 PF06581 DUF1135 Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
25 IPR007846 MPPN InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
26 PF00436 SSB Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
27 IPR003874 CDC45 InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
28 IPR001975 Ribosomal L40e InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
29 PS51472 RRM NUP35 PROSITE 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
30 G3DSA:1.10.10.350 tRNA synt bd Gene3D 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
31 G3DSA:3.20.20.370 Polysac deacetylase Gene3D 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
32 IPR005710 Ribosomal S4/S9 euk/arc InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
33 IPR006879 Uncharacterised UPF0249/HpnK InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
34 IPR020751 aa-tRNA-synth I codon-bd sub2 InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
35 PF05019 Coq4 Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
36 IPR010491 PRP1 N InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
37 PF04794 YdjC Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
38 IPR011344 ssDNA-bd InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
39 PD009396 Ribosomal L27e ProDom 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
40 IPR007715 CoenzQ biosynthesis Coq4 InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
41 IPR018079 Ribosomal S4 CS InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
42 PF02938 GAD Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
43 PF02320 UCR hinge Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
44 IPR019087 Mediator Med15 met InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
45 PF06424 PRP1 N Pfam 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
46 IPR009511 MAD2L1-bd InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
47 IPR003422 Ubol cytC Rdtase hinge InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
48 IPR002509 Polysac deacetylase InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
49 IPR001141 Ribosomal L27e InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
50 IPR004524 Asp-tRNA-synth IIb bac/mt InterPro 3.796E-3 2.827E-2
1.879E-1
1.000E0
 1 1
Show 45 more annotations

7: Pathway [Display Chart] 393 annotations before applied cutoff / 10916 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 160950 Processing of Capped Intron-Containing Pre-mRNA BioSystems: REACTOME 1.242E-6 4.879E-4 3.197E-3 4.879E-4 7 143
2 105980 tRNA Aminoacylation BioSystems: REACTOME 2.095E-5 3.584E-3 2.348E-2 8.235E-3 4 42
3 PW:0000241 schizophrenia Pathway Ontology 4.536E-5 3.584E-3 2.348E-2 1.783E-2 2 3
4 106229 snRNP Assembly BioSystems: REACTOME 4.560E-5 3.584E-3 2.348E-2 1.792E-2 4 51
5 106228 Metabolism of non-coding RNA BioSystems: REACTOME 4.560E-5 3.584E-3 2.348E-2 1.792E-2 4 51
6 105982 Mitochondrial tRNA aminoacylation BioSystems: REACTOME 7.207E-5 3.602E-3 2.360E-2 2.833E-2 3 21
7 105951 mRNA Splicing BioSystems: REACTOME 7.333E-5 3.602E-3 2.360E-2 2.882E-2 5 112
8 105952 mRNA Splicing - Major Pathway BioSystems: REACTOME 7.333E-5 3.602E-3 2.360E-2 2.882E-2 5 112
9 106068 Influenza Life Cycle BioSystems: REACTOME 9.436E-5 4.121E-3 2.700E-2 3.708E-2 6 191
10 106067 Influenza Infection BioSystems: REACTOME 1.088E-4 4.276E-3 2.802E-2 4.276E-2 6 196
11 83030 Aminoacyl-tRNA biosynthesis BioSystems: KEGG 1.260E-4 4.501E-3 2.949E-2 4.951E-2 4 66
12 530760 Antiviral mechanism by IFN-stimulated genes BioSystems: REACTOME 1.768E-4 5.151E-3 3.375E-2
6.948E-2
 4 72
13 530761 ISG15 antiviral mechanism BioSystems: REACTOME 1.768E-4 5.151E-3 3.375E-2
6.948E-2
 4 72
14 198843 mRNA processing BioSystems: WikiPathways 1.835E-4 5.151E-3 3.375E-2
7.212E-2
 5 136
15 366242 Nonsense Mediated Decay Independent of the Exon Junction Complex BioSystems: REACTOME 2.474E-4 6.406E-3 4.197E-2
9.725E-2
 5 145
16 105963 Transport of the SLBP independent Mature mRNA BioSystems: REACTOME 2.608E-4 6.406E-3 4.197E-2
1.025E-1
 3 32
17 105962 Transport of the SLBP Dependant Mature mRNA BioSystems: REACTOME 2.861E-4 6.614E-3 4.333E-2
1.124E-1
 3 33
18 187102 Negative regulators of RIG-I/MDA5 signaling BioSystems: REACTOME 3.129E-4 6.832E-3 4.476E-2
1.230E-1
 3 34
19 105964 Transport of Mature mRNA Derived from an Intronless Transcript BioSystems: REACTOME 3.413E-4 7.060E-3 4.626E-2
1.341E-1
 3 35
20 105961 Transport of Mature mRNAs Derived from Intronless Transcripts BioSystems: REACTOME 3.713E-4 7.296E-3 4.781E-2
1.459E-1
 3 36
21 366241 Nonsense Mediated Decay Enhanced by the Exon Junction Complex BioSystems: REACTOME 4.249E-4 7.590E-3 4.973E-2
1.670E-1
 5 163
22 366240 Nonsense-Mediated Decay BioSystems: REACTOME 4.249E-4 7.590E-3 4.973E-2
1.670E-1
 5 163
23 187103 Interferon Signaling BioSystems: REACTOME 5.579E-4 9.532E-3
6.246E-2
2.192E-1
 5 173
24 105953 mRNA Splicing - Minor Pathway BioSystems: REACTOME 6.296E-4 1.031E-2
6.755E-2
2.474E-1
 3 43
25 105960 Transport of Mature mRNA derived from an Intron-Containing Transcript BioSystems: REACTOME 1.100E-3 1.729E-2
1.133E-1
4.323E-1
 3 52
26 198853 Cytoplasmic Ribosomal Proteins BioSystems: WikiPathways 1.270E-3 1.919E-2
1.257E-1
4.989E-1
 4 121
27 105959 Transport of Mature Transcript to Cytoplasm BioSystems: REACTOME 1.365E-3 1.986E-2
1.302E-1
5.363E-1
 3 56
28 105995 Late Phase of HIV Life Cycle BioSystems: REACTOME 1.518E-3 2.131E-2
1.396E-1
5.967E-1
 4 127
29 83098 Parkinson's disease BioSystems: KEGG 1.702E-3 2.306E-2
1.511E-1
6.688E-1
 4 131
30 83036 Ribosome BioSystems: KEGG 1.900E-3 2.489E-2
1.631E-1
7.468E-1
 4 135
31 105984 HIV Life Cycle BioSystems: REACTOME 2.170E-3 2.509E-2
1.644E-1
8.529E-1
 4 140
32 105977 Peptide chain elongation BioSystems: REACTOME 2.170E-3 2.509E-2
1.644E-1
8.529E-1
 4 140
33 105978 Eukaryotic Translation Termination BioSystems: REACTOME 2.170E-3 2.509E-2
1.644E-1
8.529E-1
 4 140
34 106077 Viral mRNA Translation BioSystems: REACTOME 2.170E-3 2.509E-2
1.644E-1
8.529E-1
 4 140
35 105976 Eukaryotic Translation Elongation BioSystems: REACTOME 2.591E-3 2.910E-2
1.907E-1
1.000E0
 4 147
36 105968 Formation of a pool of free 40S subunits BioSystems: REACTOME 2.856E-3 3.117E-2
2.043E-1
1.000E0
 4 151
37 106074 Influenza Viral RNA Transcription and Replication BioSystems: REACTOME 3.211E-3 3.411E-2
2.235E-1
1.000E0
 4 156
38 160955 L13a-mediated translational silencing of Ceruloplasmin expression BioSystems: REACTOME 3.596E-3 3.619E-2
2.371E-1
1.000E0
 4 161
39 105973 GTP hydrolysis and joining of the 60S ribosomal subunit BioSystems: REACTOME 3.677E-3 3.619E-2
2.371E-1
1.000E0
 4 162
40 187097 RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways BioSystems: REACTOME 3.788E-3 3.619E-2
2.371E-1
1.000E0
 3 80
41 177876 RNA transport BioSystems: KEGG 3.842E-3 3.619E-2
2.371E-1
1.000E0
 4 164
42 530746 SRP-dependent cotranslational protein targeting to membrane BioSystems: REACTOME 3.926E-3 3.619E-2
2.371E-1
1.000E0
 4 165
43 105981 Cytosolic tRNA aminoacylation BioSystems: REACTOME 3.960E-3 3.619E-2
2.371E-1
1.000E0
 2 24
44 105966 Eukaryotic Translation Initiation BioSystems: REACTOME 4.276E-3 3.734E-2
2.447E-1
1.000E0
 4 169
45 105967 Cap-dependent Translation Initiation BioSystems: REACTOME 4.276E-3 3.734E-2
2.447E-1
1.000E0
 4 169
46 83046 Homologous recombination BioSystems: KEGG 5.369E-3 4.521E-2
2.963E-1
1.000E0
 2 28
47 366171 Cytokine Signaling in Immune system BioSystems: REACTOME 5.465E-3 4.521E-2
2.963E-1
1.000E0
 5 291
48 106203 Regulation of Glucokinase by Glucokinase Regulatory Protein BioSystems: REACTOME 5.752E-3 4.521E-2
2.963E-1
1.000E0
 2 29
49 106082 NEP/NS2 Interacts with the Cellular Export Machinery BioSystems: REACTOME 5.752E-3 4.521E-2
2.963E-1
1.000E0
 2 29
50 106073 Transport of Ribonucleoproteins into the Host Nucleus BioSystems: REACTOME 5.752E-3 4.521E-2
2.963E-1
1.000E0
 2 29
Show 45 more annotations

8: Pubmed [Display Chart] 3014 annotations before applied cutoff / 51818 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 22681889 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Pubmed 4.387E-12 1.322E-8 1.136E-7 1.322E-8 14 803
2 22268729 Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. Pubmed 4.582E-11 6.905E-8 5.931E-7 1.381E-7 12 613
3 22623428 Proteomic analysis of ¿4ß1 integrin adhesion complexes reveals ¿-subunit-dependent protein recruitment. Pubmed 1.467E-9 1.474E-6 1.266E-5 4.423E-6 10 491
4 15461802 A genome annotation-driven approach to cloning the human ORFeome. Pubmed 7.620E-9 5.742E-6 4.931E-5 2.297E-5 8 294
5 19738201 Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Pubmed 4.645E-8 2.800E-5 2.405E-4 1.400E-4 10 708
6 18457437 Identification of intracellular proteins associated with the EBV-encoded nuclear antigen 5 using an efficient TAP procedure and FT-ICR mass spectrometry. Pubmed 7.059E-8 3.546E-5 3.045E-4 2.128E-4 6 152
7 23398456 The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Pubmed 3.589E-7 1.496E-4 1.285E-3 1.082E-3 7 328
8 12226669 Comprehensive proteomic analysis of the human spliceosome. Pubmed 4.376E-7 1.496E-4 1.285E-3 1.319E-3 5 109
9 15231747 A protein interaction framework for human mRNA degradation. Pubmed 5.234E-7 1.496E-4 1.285E-3 1.577E-3 7 347
10 20877624 Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. Pubmed 5.461E-7 1.496E-4 1.285E-3 1.646E-3 10 926
11 20877624:gr Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. GeneRIF 5.461E-7 1.496E-4 1.285E-3 1.646E-3 10 926
12 24778252 TRIM65 regulates microRNA activity by ubiquitination of TNRC6. Pubmed 7.202E-7 1.809E-4 1.554E-3 2.171E-3 7 364
13 11875025 The human ribosomal protein genes: sequencing and comparative analysis of 73 genes. Pubmed 8.333E-7 1.911E-4 1.641E-3 2.512E-3 4 52
14 15779907 Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. Pubmed 8.875E-7 1.911E-4 1.641E-3 2.675E-3 3 14
15 23246001 SGTA recognizes a noncanonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote endoplasmic reticulum-associated degradation. Pubmed 1.008E-6 2.025E-4 1.739E-3 3.037E-3 6 239
16 21319273 An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. Pubmed 1.282E-6 2.415E-4 2.074E-3 3.864E-3 7 397
17 21630459 Proteomic characterization of the human sperm nucleus. Pubmed 2.416E-6 4.283E-4 3.679E-3 7.282E-3 7 437
18 8722009 Structure and evolution of mammalian ribosomal proteins. Pubmed 4.729E-6 7.919E-4 6.801E-3 1.425E-2 4 80
19 17620599 Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Pubmed 5.126E-6 8.131E-4 6.983E-3 1.545E-2 6 317
20 15189156 The molecular mechanics of eukaryotic translation. Pubmed 6.608E-6 9.958E-4 8.553E-3 1.992E-2 4 87
21 23455924 A Y2H-seq approach defines the human protein methyltransferase interactome. Pubmed 7.896E-6 1.133E-3 9.733E-3 2.380E-2 6 342
22 24639526 RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling. Pubmed 9.269E-6 1.215E-3 1.043E-2 2.794E-2 5 203
23 25192599 Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways. Pubmed 9.269E-6 1.215E-3 1.043E-2 2.794E-2 5 203
24 23463506 The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Pubmed 1.143E-5 1.435E-3 1.233E-2 3.445E-2 5 212
25 20458337 MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Pubmed 1.256E-5 1.514E-3 1.300E-2 3.784E-2 7 563
26 20020773 Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery. Pubmed 1.458E-5 1.676E-3 1.439E-2 4.395E-2 5 223
27 25900982 BioID-based Identification of Skp Cullin F-box (SCF)ß-TrCP1/2 E3 Ligase Substrates. Pubmed 1.555E-5 1.676E-3 1.439E-2 4.687E-2 5 226
28 7821789 Construction of a human full-length cDNA bank. Pubmed 1.557E-5 1.676E-3 1.439E-2 4.692E-2 4 108
29 12138183 Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains. Pubmed 1.846E-5 1.919E-3 1.648E-2
5.564E-2
 2 5
30 25147182 Quantitative Lys-¿-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1. Pubmed 1.938E-5 1.919E-3 1.649E-2
5.842E-2
 6 401
31 17332742 Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Pubmed 1.994E-5 1.919E-3 1.649E-2
6.010E-2
 4 115
32 25963833 Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. Pubmed 2.080E-5 1.919E-3 1.649E-2
6.270E-2
 8 845
33 23125841 Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1. Pubmed 2.116E-5 1.919E-3 1.649E-2
6.378E-2
 5 241
34 27499296 Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function. Pubmed 2.165E-5 1.919E-3 1.649E-2
6.526E-2
 6 409
35 15635413 Nucleolar proteome dynamics. Pubmed 2.478E-5 2.134E-3 1.833E-2
7.470E-2
 6 419
36 17681147 Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase. Pubmed 2.767E-5 2.296E-3 1.972E-2
8.339E-2
 2 6
37 23443559 LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. Pubmed 2.819E-5 2.296E-3 1.972E-2
8.496E-2
 7 639
38 22586326 Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Pubmed 3.234E-5 2.565E-3 2.203E-2
9.746E-2
 7 653
39 12962325 Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing. Pubmed 4.079E-5 3.073E-3 2.639E-2
1.229E-1
 3 48
40 14567916 Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. Pubmed 4.079E-5 3.073E-3 2.639E-2
1.229E-1
 3 48
41 7772601 Cloning, sequencing and expression of the L5, L21, L27a, L28, S5, S9, S10 and S29 human ribosomal protein mRNAs. Pubmed 5.155E-5 3.790E-3 3.255E-2
1.554E-1
 2 8
42 22678362 MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. Pubmed 5.636E-5 3.829E-3 3.288E-2
1.699E-1
 4 150
43 16009940 Human ISG15 conjugation targets both IFN-induced and constitutively expressed proteins functioning in diverse cellular pathways. Pubmed 5.934E-5 3.829E-3 3.288E-2
1.788E-1
 4 152
44 11751223 Differential expression of genes coding for ribosomal proteins in different human tissues. Pubmed 6.622E-5 3.829E-3 3.288E-2
1.996E-1
 2 9
45 22751105 Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress. Pubmed 7.066E-5 3.829E-3 3.288E-2
2.130E-1
 4 159
46 24797263 Proteomic analysis of the epidermal growth factor receptor (EGFR) interactome and post-translational modifications associated with receptor endocytosis in response to EGF and stress. Pubmed 8.481E-5 3.829E-3 3.288E-2
2.556E-1
 5 323
47 24332808 PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry. Pubmed 1.078E-4 3.829E-3 3.288E-2
3.250E-1
 5 340
48 9582194 A map of 75 human ribosomal protein genes. Pubmed 1.109E-4 3.829E-3 3.288E-2
3.342E-1
 3 67
49 22365833 Dynamic protein-protein interaction wiring of the human spliceosome. Pubmed 1.613E-4 3.829E-3 3.288E-2
4.862E-1
 4 197
50 25609649 Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Pubmed 1.656E-4 3.829E-3 3.288E-2
4.990E-1
 7 849
Show 45 more annotations

9: Interaction [Display Chart] 2057 annotations before applied cutoff / 16535 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:CUL5 CUL5 interactions 1.846E-7 3.797E-4 3.116E-3 3.797E-4 12 429
2 int:DDX18 DDX18 interactions 4.401E-6 4.336E-3 3.558E-2 9.054E-3 6 103
3 int:HNRNPU HNRNPU interactions 9.035E-6 4.336E-3 3.558E-2 1.859E-2 11 518
4 int:FBXO6 FBXO6 interactions 9.082E-6 4.336E-3 3.558E-2 1.868E-2 12 623
5 int:RPL10 RPL10 interactions 1.054E-5 4.336E-3 3.558E-2 2.168E-2 9 337
6 int:RPL32 RPL32 interactions 2.612E-5 8.955E-3
7.349E-2
5.373E-2
 5 84
7 int:NPM1 NPM1 interactions 3.270E-5 9.609E-3
7.885E-2
6.726E-2
 11 595
8 int:RPL26 RPL26 interactions 4.732E-5 1.024E-2
8.400E-2
9.734E-2
 5 95
9 int:ITGA4 ITGA4 interactions 4.974E-5 1.024E-2
8.400E-2
1.023E-1
 10 513
10 int:UPF2 UPF2 interactions 4.976E-5 1.024E-2
8.400E-2
1.024E-1
 5 96
11 int:PRPF4B PRPF4B interactions 7.504E-5 1.322E-2
1.085E-1
1.544E-1
 4 54
12 int:ILF3 ILF3 interactions 7.927E-5 1.322E-2
1.085E-1
1.631E-1
 8 338
13 int:RPS7 RPS7 interactions 8.355E-5 1.322E-2
1.085E-1
1.719E-1
 6 173
14 int:VCAM1 VCAM1 interactions 9.575E-5 1.407E-2
1.154E-1
1.970E-1
 9 447
15 int:FAU FAU interactions 1.135E-4 1.471E-2
1.207E-1
2.336E-1
 4 60
16 int:ASB1 ASB1 interactions 1.160E-4 1.471E-2
1.207E-1
2.386E-1
 3 23
17 int:CAND1 CAND1 interactions 1.302E-4 1.471E-2
1.207E-1
2.677E-1
 11 694
18 int:RPL36 RPL36 interactions 1.327E-4 1.471E-2
1.207E-1
2.730E-1
 5 118
19 int:RPL4 RPL4 interactions 1.358E-4 1.471E-2
1.207E-1
2.794E-1
 6 189
20 int:RPL13 RPL13 interactions 1.899E-4 1.953E-2
1.603E-1
3.907E-1
 6 201
21 int:MRPS16 MRPS16 interactions 2.114E-4 2.071E-2
1.699E-1
4.349E-1
 3 28
22 int:UBL4A UBL4A interactions 2.388E-4 2.233E-2
1.832E-1
4.912E-1
 7 298
23 int:RPL37 RPL37 interactions 2.875E-4 2.571E-2
2.110E-1
5.914E-1
 3 31
24 int:RPS23 RPS23 interactions 3.465E-4 2.890E-2
2.372E-1
7.127E-1
 5 145
25 int:RPS24 RPS24 interactions 3.576E-4 2.890E-2
2.372E-1
7.356E-1
 5 146
26 int:RPL18A RPL18A interactions 3.690E-4 2.890E-2
2.372E-1
7.590E-1
 5 147
27 int:LIN28B LIN28B interactions 3.793E-4 2.890E-2
2.372E-1
7.803E-1
 3 34
28 int:RPS25 RPS25 interactions 4.174E-4 2.951E-2
2.422E-1
8.586E-1
 5 151
29 int:FUS FUS interactions 4.263E-4 2.951E-2
2.422E-1
8.769E-1
 7 328
30 int:RPL35A RPL35A interactions 4.558E-4 2.951E-2
2.422E-1
9.376E-1
 4 86
31 int:RPL34 RPL34 interactions 4.558E-4 2.951E-2
2.422E-1
9.376E-1
 4 86
32 int:DCUN1D1 DCUN1D1 interactions 4.592E-4 2.951E-2
2.422E-1
9.445E-1
 6 237
33 int:RPS20 RPS20 interactions 4.844E-4 3.005E-2
2.466E-1
9.965E-1
 5 156
34 int:CUL1 CUL1 interactions 4.967E-4 3.005E-2
2.466E-1
1.000E0
 10 681
35 int:PAN2 PAN2 interactions 5.663E-4 3.261E-2
2.676E-1
1.000E0
 7 344
36 int:RPL3L RPL3L interactions 5.707E-4 3.261E-2
2.676E-1
1.000E0
 3 39
37 int:RPL26L1 RPL26L1 interactions 5.886E-4 3.272E-2
2.685E-1
1.000E0
 4 92
38 int:HNRNPM HNRNPM interactions 6.084E-4 3.293E-2
2.703E-1
1.000E0
 6 250
39 int:RPS19 RPS19 interactions 6.968E-4 3.615E-2
2.967E-1
1.000E0
 5 169
40 int:NPLOC4 NPLOC4 interactions 7.185E-4 3.615E-2
2.967E-1
1.000E0
 4 97
41 int:RPS14 RPS14 interactions 7.544E-4 3.615E-2
2.967E-1
1.000E0
 5 172
42 int:CD7 CD7 interactions 7.558E-4 3.615E-2
2.967E-1
1.000E0
 2 10
43 int:ASH1L ASH1L interactions 7.558E-4 3.615E-2
2.967E-1
1.000E0
 2 10
44 int:RPS8 RPS8 interactions 8.576E-4 4.009E-2
3.290E-1
1.000E0
 6 267
45 int:RPL7 RPL7 interactions 8.802E-4 4.024E-2
3.302E-1
1.000E0
 5 178
46 int:ZNF764 ZNF764 interactions 9.212E-4 4.120E-2
3.381E-1
1.000E0
 2 11
47 int:RPS2 RPS2 interactions 9.622E-4 4.211E-2
3.456E-1
1.000E0
 6 273
48 int:OBSL1 OBSL1 interactions 1.005E-3 4.306E-2
3.534E-1
1.000E0
 9 616
49 int:HARS HARS interactions 1.185E-3 4.701E-2
3.858E-1
1.000E0
 3 50
50 int:MPV17 MPV17 interactions 1.185E-3 4.701E-2
3.858E-1
1.000E0
 3 50
Show 45 more annotations

10: Cytoband [Display Chart] 56 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 22q11.21 22q11.21 6.206E-9 3.475E-7 1.603E-6 3.475E-7 7 122
2 22q11.22 22q11.22 1.018E-3 2.850E-2
1.314E-1
5.700E-2
 2 23
3 22q11.2 22q11.2 1.995E-3 3.299E-2
1.521E-1
1.117E-1
 3 121
4 1q25.1 1q25.1 2.356E-3 3.299E-2
1.521E-1
1.319E-1
 2 35
5 19p13.1-p12 19p13.1-p12 4.093E-3 4.584E-2
2.114E-1
2.292E-1
 1 2

11: Transcription Factor Binding Site [Display Chart] 298 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CCCNNNNNNAAGWT UNKNOWN CCCNNNNNNAAGWT UNKNOWN 3.024E-5 9.011E-3
5.655E-2
 9.011E-3 5 78
2 V$E2F1 Q6 01 V$E2F1 Q6 01 2.382E-4 3.550E-2
2.228E-1
7.099E-2
 6 189

12: Gene Family [Display Chart] 12 annotations before applied cutoff / 6751 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 KLHL Kelch-like family genenames.org 2.314E-3 2.777E-2
8.618E-2
 2.777E-2 2 38

13: Coexpression [Display Chart] 3732 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M4772 Genes up-regulated in robust Cluster 2 (rC2) of hepatoblastoma samples compared to those in the robust Cluster 1 (rC1). MSigDB C2: CGP Curated Gene Sets (v5.1) 6.532E-8 2.438E-4 2.146E-3 2.438E-4 13 605
2 M19988 Genes down-regulated in metastatic breast cancer tumors having type 2 amplification in the 20q13 region; involves MYBL2, STK6 and ZNF217 [GeneID=4605;6790;7764] MSigDB C2: CGP Curated Gene Sets (v5.1) 1.944E-6 3.367E-3 2.964E-2 7.254E-3 7 180
3 M2099 Genes down-regulated in NB4 cells (acute promyelocytic leukemia, APL) in response to tretinoin [PubChem=444795]; based on Chip-seq data. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.707E-6 3.367E-3 2.964E-2 1.010E-2 13 841
4 M5926 A subgroup of genes regulated by MYC - version 1 (v1). MSigDB H: Hallmark Gene Sets (v5.1) 3.907E-6 3.645E-3 3.209E-2 1.458E-2 7 200
5 M10633 Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.108E-6 5.305E-3 4.670E-2 2.653E-2 6 143
6 M14524 Up-regulated genes in colon carcinoma tumors compared to the matched normal mucosa samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.149E-5 1.336E-2
1.176E-1
8.019E-2
 12 870
7 M19907 Genes down-regulated in HL-60 cells (acute promyelocytic leukemia, APL) after treatment with the aminopeptidase inhibitor tosedostat (CHR-2797) [PubChem=15547703] for 6 h. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.375E-5 1.490E-2
1.312E-1
1.259E-1
 12 911
8 M12664 Cluster 3: genes changed in primary keratinocytes by UVB irradiation. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.594E-5 1.490E-2
1.312E-1
1.341E-1
 3 20
9 M17954 Genes down-regulated in hyppocampus of mice carrying a hemizygotic microdeletion in the 22q11.2 region. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.594E-5 1.490E-2
1.312E-1
1.341E-1
 3 20
10 M5170 Genes up-regulated in comparison of macrophages versus macrophages exposed to M. tuberculosis. MSigDB C7: Immunologic Signatures (v5.1) 4.614E-5 1.610E-2
1.417E-1
1.722E-1
 6 199
11 M3947 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 8 h. MSigDB C7: Immunologic Signatures (v5.1) 4.744E-5 1.610E-2
1.417E-1
1.771E-1
 6 200
12 M1806 Direct targets of FOXA2 [GeneID=3170] in liver, according to a ChIP-chip analysis. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.955E-5 2.163E-2
1.904E-1
2.596E-1
 8 425
13 M2428 Down-regulated by induction of exogenous BRCA1 in EcR-293 cells MSigDB C2: CGP Curated Gene Sets (v5.1) 9.603E-5 2.757E-2
2.426E-1
3.584E-1
 5 141
Show 8 more annotations

14: Coexpression Atlas [Display Chart] 1387 annotations before applied cutoff / 20974 genes in category

No results to display

15: Computational [Display Chart] 296 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 module 83 Genes in module 83 MSigDb: C4 - CM: Cancer Modules 7.513E-5 1.167E-2
7.313E-2
 2.224E-2 8 307
2 GNF2 DAP3 Neighborhood of DAP3 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.109E-4 1.167E-2
7.313E-2
 3.282E-2 5 103
3 GNF2 EIF3S6 Neighborhood of EIF3S6 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.513E-4 1.167E-2
7.313E-2
 4.479E-2 5 110
4 GNF2 NPM1 Neighborhood of NPM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.576E-4 1.167E-2
7.313E-2
 4.666E-2 4 59
5 GNF2 APEX1 Neighborhood of APEX1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 4.409E-4 2.610E-2
1.636E-1
1.305E-1
 4 77
6 GNF2 UBE2I Neighborhood of UBE2I MSigDb: C4 - CGN: Cancer Gene Neighborhood 5.643E-4 2.784E-2
1.745E-1
1.670E-1
 3 35
7 MORF BUB3 Neighborhood of BUB3 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.235E-3 4.269E-2
2.677E-1
3.656E-1
 6 260
8 GNF2 DEK Neighborhood of DEK MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.429E-3 4.269E-2
2.677E-1
4.231E-1
 3 48
9 MORF BUB1 Neighborhood of BUB1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.609E-3 4.269E-2
2.677E-1
4.763E-1
 3 50
10 GCM NPM1 Neighborhood of NPM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.626E-3 4.269E-2
2.677E-1
4.813E-1
 4 109
11 module 429 Genes in module 429 MSigDb: C4 - CM: Cancer Modules 1.881E-3 4.269E-2
2.677E-1
5.567E-1
 2 14
12 GCM ACTG1 Neighborhood of ACTG1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 1.980E-3 4.269E-2
2.677E-1
5.861E-1
 4 115
13 module 110 Genes in module 110 MSigDb: C4 - CM: Cancer Modules 2.164E-3 4.269E-2
2.677E-1
6.404E-1
 2 15
14 module 133 Genes in module 133 MSigDb: C4 - CM: Cancer Modules 2.164E-3 4.269E-2
2.677E-1
6.404E-1
 2 15
15 module 160 Genes in module 160 MSigDb: C4 - CM: Cancer Modules 2.164E-3 4.269E-2
2.677E-1
6.404E-1
 2 15
16 MORF EIF4A2 Neighborhood of EIF4A2 MSigDb: C4 - CGN: Cancer Gene Neighborhood 2.457E-3 4.293E-2
2.691E-1
7.272E-1
 4 122
17 module 35 Genes in module 35 MSigDb: C4 - CM: Cancer Modules 2.465E-3 4.293E-2
2.691E-1
7.297E-1
 2 16
18 MORF UBE2I Neighborhood of UBE2I MSigDb: C4 - CGN: Cancer Gene Neighborhood 3.018E-3 4.963E-2
3.111E-1
8.933E-1
 5 213
Show 13 more annotations

16: MicroRNA [Display Chart] 1411 annotations before applied cutoff / 19844 genes in category

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17: Drug [Display Chart] 9757 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1893 DN Doxylamine succinate [562-10-7]; Down 200; 10.2uM; PC3; HG-U133A Broad Institute CMAP 2.367E-7 2.309E-3 2.254E-2 2.309E-3 8 198

18: Disease [Display Chart] 559 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C0220704 Shprintzen syndrome DisGeNET Curated 8.687E-7 2.877E-4 1.986E-3 4.856E-4 5 56
2 umls:C3266101 22q11 partial monosomy syndrome DisGeNET Curated 1.029E-6 2.877E-4 1.986E-3 5.753E-4 3 7
3 umls:C0012236 DiGeorge Syndrome DisGeNET Curated 2.858E-6 5.324E-4 3.676E-3 1.597E-3 5 71
4 umls:C0026847 Spinal Muscular Atrophy DisGeNET Curated 1.151E-5 1.609E-3 1.111E-2 6.436E-3 6 162
5 umls:C0795907 CONOTRUNCAL ANOMALY FACE SYNDROME DisGeNET Curated 2.033E-4 2.272E-2
1.569E-1
1.136E-1
 2 7