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1: GO: Molecular Function [Display Chart] 236 annotations before applied cutoff / 18819 genes in category

No results to display

2: GO: Biological Process [Display Chart] 955 annotations before applied cutoff / 18785 genes in category

No results to display

3: GO: Cellular Component [Display Chart] 185 annotations before applied cutoff / 19172 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:1990904 ribonucleoprotein complex 2.613E-4 2.417E-2
1.402E-1
 4.833E-2 9 751
2 GO:0030529 intracellular ribonucleoprotein complex 2.613E-4 2.417E-2
1.402E-1
 4.833E-2 9 751
3 GO:0005844 polysome 4.469E-4 2.756E-2
1.599E-1
8.268E-2
 3 52

4: Human Phenotype [Display Chart] 67 annotations before applied cutoff / 1813 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0200044 Porokeratosis 3.645E-5 2.442E-3 1.170E-2 2.442E-3 2 4

5: Mouse Phenotype [Display Chart] 683 annotations before applied cutoff / 9208 genes in category

No results to display

6: Domain [Display Chart] 334 annotations before applied cutoff / 16924 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF04112 Mak10 Pfam 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
2 PF08524 rRNA processing Pfam 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
3 IPR019716 Ribosomal L53 mit InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
4 IPR018260 Ribosomal L22/L17 CS InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
5 IPR016453 Coatomer beta' subunit InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
6 PF04121 Nup84 Nup100 Pfam 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
7 IPR009149 BR22 InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
8 IPR005721 Ribosomal L22/L17 euk/arc InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
9 PF10780 MRP L53 Pfam 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
10 IPR007244 NatC a AcTrfase InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
11 IPR013296 HSPB1-associated protein 1 InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
12 IPR007128 Nnf1 InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
13 PF04275 P-mevalo kinase Pfam 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
14 IPR018397 Lysosomal-assoc TM prot5 InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
15 IPR008669 Lsm interact InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
16 IPR005919 Pmev kin anim InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
17 PF03980 Nnf1 Pfam 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
18 IPR017334 Transl init eIF-3 RNA-bind InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
19 IPR007252 Nup84 Nup100 InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
20 PF05391 Lsm interact Pfam 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
21 IPR013730 rRNA processing InterPro 2.963E-3 4.692E-2
2.998E-1
9.896E-1
 1 1
22 PS51015 YDG PROSITE 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
23 IPR018396 Mtp transporter mml InterPro 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
24 IPR003105 SRA YDG InterPro 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
25 IPR006722 Sedlin InterPro 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
26 PF04628 Sedlin N Pfam 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
27 PF00237 Ribosomal L22 Pfam 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
28 PF09177 Syntaxin-6 N Pfam 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
29 G3DSA:3.90.470.10 Ribosomal L22 Gene3D 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
30 IPR013932 TATA-bd TIP120 InterPro 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
31 SM00438 ZnF NFX SMART 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
32 IPR015260 Syntaxin-6 N InterPro 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
33 IPR006692 Coatomer WD-assoc reg InterPro 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
34 PF02182 YDG SRA Pfam 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
35 IPR021991 DUF3590 InterPro 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
36 PF06068 TIP49 Pfam 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
37 PF12148 DUF3590 Pfam 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
38 PS00464 RIBOSOMAL L22 PROSITE 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
39 PF08623 TIP120 Pfam 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
40 SM00466 SRA SMART 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
41 PF04053 Coatomer WDAD Pfam 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
42 IPR010339 TIP49 C InterPro 5.900E-3 4.692E-2
2.998E-1
1.000E0
 1 2
Show 37 more annotations

7: Pathway [Display Chart] 401 annotations before applied cutoff / 10916 genes in category

No results to display

8: Pubmed [Display Chart] 2972 annotations before applied cutoff / 51818 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 16196087 Large-scale analysis of the human ubiquitin-related proteome. Pubmed 6.336E-8 1.883E-4 1.615E-3 1.883E-4 7 313
2 21890473 A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. Pubmed 1.361E-7 2.023E-4 1.735E-3 4.046E-4 6 209
3 21139048 Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. Pubmed 2.580E-7 2.082E-4 1.785E-3 7.667E-4 6 233
4 17643375 Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme. Pubmed 2.802E-7 2.082E-4 1.785E-3 8.327E-4 7 390
5 22032989 CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination. Pubmed 4.801E-7 2.854E-4 2.447E-3 1.427E-3 3 14
6 14743216 A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. Pubmed 1.125E-6 4.579E-4 3.926E-3 3.343E-3 5 162
7 16815301:gr Induction of CML28-specific cytotoxic T cell responses using co-transfected dendritic cells with CML28 DNA vaccine and SOCS1 small interfering RNA expression vector. GeneRIF 1.233E-6 4.579E-4 3.926E-3 3.663E-3 2 2
8 16815301 Induction of CML28-specific cytotoxic T cell responses using co-transfected dendritic cells with CML28 DNA vaccine and SOCS1 small interfering RNA expression vector. Pubmed 1.233E-6 4.579E-4 3.926E-3 3.663E-3 2 2
9 24816145 A COFRADIC protocol to study protein ubiquitination. Pubmed 1.468E-6 4.847E-4 4.156E-3 4.362E-3 5 171
10 17761535 Functional characterization of the OFD1 protein reveals a nuclear localization and physical interaction with subunits of a chromatin remodeling complex. Pubmed 3.691E-6 9.756E-4 8.365E-3 1.097E-2 2 3
11 21906983 Systematic and quantitative assessment of the ubiquitin-modified proteome. Pubmed 3.739E-6 9.756E-4 8.365E-3 1.111E-2 5 207
12 20467437 Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice. Pubmed 3.939E-6 9.756E-4 8.365E-3 1.171E-2 7 581
13 25609649 Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Pubmed 4.673E-6 1.068E-3 9.160E-3 1.389E-2 8 849
14 22268729 Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells. Pubmed 5.588E-6 1.186E-3 1.017E-2 1.661E-2 7 613
15 19690564 A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system. Pubmed 9.531E-6 1.759E-3 1.508E-2 2.833E-2 4 117
16 21630459 Proteomic characterization of the human sperm nucleus. Pubmed 9.712E-6 1.759E-3 1.508E-2 2.886E-2 6 437
17 23658844 The novel ubiquitin ligase complex, SCF(Fbxw4), interacts with the COP9 signalosome in an F-box dependent manner, is mutated, lost and under-expressed in human cancers. Pubmed 1.006E-5 1.759E-3 1.508E-2 2.991E-2 3 37
18 22505724 Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. Pubmed 1.880E-5 3.104E-3 2.661E-2
5.586E-2
 4 139
19 20595234 The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome. Pubmed 3.433E-5 3.936E-3 3.375E-2
1.020E-1
 2 8
20 23000965 Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. Pubmed 3.765E-5 3.936E-3 3.375E-2
1.119E-1
 4 166
21 21963094 Global identification of modular cullin-RING ligase substrates. Pubmed 4.941E-5 3.936E-3 3.375E-2
1.468E-1
 4 178
22 25882842 CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation. Pubmed 5.509E-5 3.936E-3 3.375E-2
1.637E-1
 2 10
23 25852190 Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. Pubmed 8.855E-5 3.936E-3 3.375E-2
2.632E-1
 5 401
24 25147182 Quantitative Lys-¿-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1. Pubmed 8.855E-5 3.936E-3 3.375E-2
2.632E-1
 5 401
25 17314511 Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach. Pubmed 9.369E-5 3.936E-3 3.375E-2
2.784E-1
 4 210
26 9253601 A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus. Pubmed 9.528E-5 3.936E-3 3.375E-2
2.832E-1
 2 13
27 22767593 Deconjugation of Nedd8 from Cul1 is directly regulated by Skp1-F-box and substrate, and the COP9 signalosome inhibits deneddylated SCF by a noncatalytic mechanism. Pubmed 9.528E-5 3.936E-3 3.375E-2
2.832E-1
 2 13
28 23463506 The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes. Pubmed 9.718E-5 3.936E-3 3.375E-2
2.888E-1
 4 212
29 20833797 Phosphoproteome analysis of functional mitochondria isolated from resting human muscle reveals extensive phosphorylation of inner membrane protein complexes and enzymes. Pubmed 1.067E-4 3.936E-3 3.375E-2
3.171E-1
 3 81
30 20562859 Network organization of the human autophagy system. Pubmed 1.254E-4 3.936E-3 3.375E-2
3.726E-1
 5 432
31 18606781 Human immunodeficiency virus type 1 Vpr-binding protein VprBP, a WD40 protein associated with the DDB1-CUL4 E3 ubiquitin ligase, is essential for DNA replication and embryonic development. Pubmed 1.281E-4 3.936E-3 3.375E-2
3.806E-1
 2 15
32 16036220 CAND1 enhances deneddylation of CUL1 by COP9 signalosome. Pubmed 1.463E-4 3.936E-3 3.375E-2
4.347E-1
 2 16
33 14690596 Regulation of NF-kappaB signaling by Pin1-dependent prolyl isomerization and ubiquitin-mediated proteolysis of p65/RelA. Pubmed 1.463E-4 3.936E-3 3.375E-2
4.347E-1
 2 16
34 22190034 Global landscape of HIV-human protein complexes. Pubmed 1.628E-4 3.936E-3 3.375E-2
4.839E-1
 5 457
35 21081666 Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation. Pubmed 2.062E-4 3.936E-3 3.375E-2
6.129E-1
 4 258
36 17403899 CIF-1, a shared subunit of the COP9/signalosome and eukaryotic initiation factor 3 complexes, regulates MEL-26 levels in the Caenorhabditis elegans embryo. Pubmed 2.551E-4 3.936E-3 3.375E-2
7.580E-1
 2 21
37 11719186 AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. Pubmed 2.551E-4 3.936E-3 3.375E-2
7.580E-1
 2 21
38 18187620 Identification of host proteins required for HIV infection through a functional genomic screen. Pubmed 2.556E-4 3.936E-3 3.375E-2
7.598E-1
 4 273
39 22681889 The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Pubmed 2.773E-4 3.936E-3 3.375E-2
8.242E-1
 6 803
40 21549307 Maintenance of silent chromatin through replication requires SWI/SNF-like chromatin remodeler SMARCAD1. Pubmed 3.162E-4 3.936E-3 3.375E-2
9.397E-1
 3 117
41 17079684 DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases. Pubmed 4.568E-4 3.936E-3 3.375E-2
1.000E0
 2 28
42 25943894 1Differential immune mechanism to HIV-1 Tat variants and its regulation by AEA. Pubmed 4.568E-4 3.936E-3 3.375E-2
1.000E0
 2 28
43 26752685 FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1. Pubmed 4.909E-4 3.936E-3 3.375E-2
1.000E0
 3 136
44 23398456 The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability. Pubmed 5.109E-4 3.936E-3 3.375E-2
1.000E0
 4 328
45 19490893 A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene. Pubmed 5.406E-4 3.936E-3 3.375E-2
1.000E0
 4 333
46 19549727 Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. Pubmed 5.798E-4 3.936E-3 3.375E-2
1.000E0
 3 144
47 16503656 Analysis of Nedd8-associated polypeptides: a model for deciphering the pathway for ubiquitin-like modifications. Pubmed 5.977E-4 3.936E-3 3.375E-2
1.000E0
 2 32
48 17267499 NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells. Pubmed 5.977E-4 3.936E-3 3.375E-2
1.000E0
 2 32
49 16964240 Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery. Pubmed 5.977E-4 3.936E-3 3.375E-2
1.000E0
 2 32
50 15231747 A protein interaction framework for human mRNA degradation. Pubmed 6.306E-4 3.936E-3 3.375E-2
1.000E0
 4 347
Show 45 more annotations

9: Interaction [Display Chart] 2470 annotations before applied cutoff / 16535 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:CHAF1A CHAF1A interactions 6.009E-6 1.484E-2
1.245E-1
 1.484E-2 7 215
2 int:RNF167 RNF167 interactions 1.457E-5 1.737E-2
1.457E-1
 3.599E-2 3 15
3 int:FBXW4 FBXW4 interactions 2.448E-5 1.737E-2
1.457E-1
6.047E-2
 4 52
4 int:MEPCE MEPCE interactions 2.813E-5 1.737E-2
1.457E-1
6.949E-2
 6 183
5 int:TRIM10 TRIM10 interactions 8.117E-5 4.010E-2
3.364E-1
2.005E-1
 3 26
6 int:DDA1 DDA1 interactions 1.095E-4 4.507E-2
3.782E-1
2.704E-1
 4 76
7 int:HERC1 HERC1 interactions 1.387E-4 4.895E-2
4.106E-1
3.426E-1
 3 31
Show 2 more annotations

10: Cytoband [Display Chart] 52 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 11p15.3 11p15.3 6.807E-4 2.445E-2
1.109E-1
 3.539E-2 2 23
2 Xp22 Xp22 9.403E-4 2.445E-2
1.109E-1
 4.889E-2 2 27
3 10q26.2-q26.3 10q26.2-q26.3 1.676E-3 2.905E-2
1.318E-1
8.716E-2
 1 1
4 19q13.1 19q13.1 3.860E-3 4.691E-2
2.129E-1
2.007E-1
 2 55
5 11q13.1 11q13.1 5.674E-3 4.691E-2
2.129E-1
2.951E-1
 2 67
6 10q24-q25 10q24-q25 6.677E-3 4.691E-2
2.129E-1
3.472E-1
 1 4
7 13q11-q12 13q11-q12 6.677E-3 4.691E-2
2.129E-1
3.472E-1
 1 4
8 19p13.2 19p13.2 7.216E-3 4.691E-2
2.129E-1
3.752E-1
 3 235
Show 3 more annotations

11: Transcription Factor Binding Site [Display Chart] 295 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 TMTCGCGANR UNKNOWN TMTCGCGANR UNKNOWN 4.324E-9 1.275E-6 7.992E-6 1.275E-6 8 109

12: Gene Family [Display Chart] 10 annotations before applied cutoff / 6751 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MXD MAX dimerization proteins genenames.org 8.858E-3 2.582E-2
7.562E-2
8.858E-2
 1 6
2 ZBED Zinc fingers, BED-type genenames.org 8.858E-3 2.582E-2
7.562E-2
8.858E-2
 1 6
3 ZMYM Zinc fingers, MYM-type genenames.org 8.858E-3 2.582E-2
7.562E-2
8.858E-2
 1 6
4 YIPF Yip1 domain family genenames.org 1.033E-2 2.582E-2
7.562E-2
1.033E-1
 1 7

13: Coexpression [Display Chart] 3359 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M1918 Up-regulated genes in pediatric adrenocortical tumors (ACT) compared to the normal tissue. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.124E-4 3.880E-2
3.374E-1
3.776E-1
 6 293
2 M123 Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells, embryonical carcinomas and induced pluripotent cells). MSigDB C2: CGP Curated Gene Sets (v5.1) 1.256E-4 3.880E-2
3.374E-1
4.218E-1
 6 299
3 GSE20198 IL12 IL18 VS IFNA TREATED ACT CD4 TCELL DN Genes down-regulated in the activated CD4 [GeneID=920] T cells (48h): IL-12 and IL18 [GeneID=3606] versus interferon alpha. MSigDB C7: Immunologic Signatures (v5.1) 1.693E-4 3.880E-2
3.374E-1
5.686E-1
 5 199
4 GSE25088 IL4 VS IL4 AND ROSIGLITAZONE STIM STAT6 KO MACROPHAGE DAY10 DN Genes down-regulated in bone marrow-derived macrophages with STAT6 [GeneID=6778] knockout treated with IL4 [GeneID=3565]: control versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v5.1) 1.693E-4 3.880E-2
3.374E-1
5.686E-1
 5 199
5 M6079 Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus IL4 [GeneID=3565] (2h). MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
6 GSE23505 IL6 IL1 VS IL6 IL1 TGFB TREATED CD4 TCELL UP Genes up-regulated in CD4 [GeneID=920] T cells treated with IL1B and IL6 [GeneID=3553;3569] versus those also treated with TGFB1 [GeneID=7040]. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
7 GSE26343 UNSTIM VS LPS STIM NFAT5 KO MACROPHAGE UP Genes up-regulated in bone marrow-derived macrophages with NFAT5 [GeneID=10725] knockout: control versus stimulated with LPS. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
8 M4527 Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th2 cells at 12 h. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
9 M6202 Genes down-regulated in polymorphonuclear leukocytes (9h): control versus infection by A. phagocytophilum. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
10 M5726 Genes down-regulated in comparison of NK cells treated with IL15 [GeneID=3567] versus total splenocytes. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
11 GSE23308 CTRL VS CORTICOSTERONE TREATED MACROPHAGE MINERALCORTICOID REC KO DN Genes down-regulated in macrophages with NR3C2 [GeneID=4306] knockout: untreated versus corticosterone [PubChem=5839]. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
12 M6363 Genes up-regulated in dendiritic cells from speen: interferon producing killer cells versus conventional. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
13 M6204 Genes up-regulated in polymorphonuclear leukocytes (24h): control versus infection by A. phagocytophilum. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
14 GSE32986 CURDLAN HIGHDOSE VS GMCSF AND CURDLAN HIGHDOSE STIM DC DN Genes down-regulated in bone marrow-derived dendritic cells: high dose of 1,3-beta-D-oligoglucan [PubChem=11375554] versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
15 GSE43260 BTLA POS VS NEG INTRATUMORAL CD8 TCELL DN Genes down-regulated in tumor-infiltrating CD8 T cells: BTLA+ [GeneID=151888] versus BTLA- [GeneID=151888]. MSigDB C7: Immunologic Signatures (v5.1) 1.733E-4 3.880E-2
3.374E-1
5.820E-1
 5 200
Show 10 more annotations

14: Coexpression Atlas [Display Chart] 1287 annotations before applied cutoff / 20974 genes in category

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15: Computational [Display Chart] 274 annotations before applied cutoff / 9399 genes in category

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16: MicroRNA [Display Chart] 1305 annotations before applied cutoff / 19844 genes in category

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17: Drug [Display Chart] 5675 annotations before applied cutoff / 22098 genes in category

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18: Disease [Display Chart] 343 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C1333280 Desmoplastic melanoma DisGeNET BeFree 4.819E-4 4.157E-2
2.667E-1
1.653E-1
 2 13
2 umls:C1959629 Seizure Adverse Event DisGeNET Curated 1.046E-3 4.157E-2
2.667E-1
3.589E-1
 2 19
3 umls:C3839280 High grade serous carcinoma DisGeNET BeFree 1.407E-3 4.157E-2
2.667E-1
4.825E-1
 2 22
4 umls:C1567435 Polycystic Kidney - body part DisGeNET BeFree 1.818E-3 4.157E-2
2.667E-1
6.236E-1
 2 25
5 cv:C0220776 Spondyloepiphyseal dysplasia tarda Clinical Variations 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
6 umls:C2749019 JOUBERT SYNDROME 10 (disorder) DisGeNET Curated 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
7 311200 OROFACIODIGITAL SYNDROME I; OFD1 OMIM 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
8 cv:C2749019 Joubert syndrome 10 Clinical Variations 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
9 cv:C1846175 Simpson-Golabi-Behmel syndrome, type 2 Clinical Variations 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
10 313400 SPONDYLOEPIPHYSEAL DYSPLASIA TARDA, X-LINKED; SEDT OMIM 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
11 cv:C1510460 Oral-facial-digital syndrome Clinical Variations 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
12 300209 SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 2 OMIM 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
13 umls:C1857512 Temtamy syndrome DisGeNET Curated 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
14 cv:C1845542 Retinitis Pigmentosa 23 Clinical Variations 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
15 300804 JOUBERT SYNDROME 10; JBTS10 OMIM 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
16 cv:C1857512 Temtamy syndrome Clinical Variations 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
17 cv:CN224984 Mental retardation, autosomal dominant 31 Clinical Variations 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
18 umls:C4015357 MENTAL RETARDATION, AUTOSOMAL DOMINANT 31 DisGeNET Curated 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
19 umls:C1846175 SIMPSON-GOLABI-BEHMEL SYNDROME, TYPE 2 (disorder) DisGeNET Curated 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
20 umls:C1855369 Maple Syrup Urine Disease, Type IA DisGeNET Curated 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
21 cv:CN228784 MITOCHONDRIAL SHORT-CHAIN ENOYL-CoA HYDRATASE 1 DEFICIENCY Clinical Variations 2.545E-3 4.157E-2
2.667E-1
8.729E-1
 1 1
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