On Explicit Models of Emergent Space

I will describe general ideas that lead to the explicit constructions of models of emergent space. In particular, I will solve a pre-geometric quantum mechanical model for D-particles in a presence of a large number of background D4 branes, and show that it is equivalent to the classical motion of the particles in the ten dimensional geometry sourced by the D4 branes. If time allows, other cases will be briefly discussed as well.

Sur les g-fractions de Wall : de Ramanujan à Poincaré [G-fractions of Wall : from Ramanujan conjecture to Three-Body problem]

Résumé : En 1948 H.S. Wall a publié ses résultats sur la théorie analytique des fractions continues. Dans la première partie de cet exposé nous présentons une classe remarquable de fractions continues introduite par Wall et appelées g-fractions. Nous montrerons comment elles peuvent être utilisées pour approcher certaines applications analytiques bornées réelles.
La deuxième partie de l’exposé sera consacrée aux applications de cette méthode. Nous discuterons de la conjecture de Ramanujan portant sur la convergence d’une des fractions continues, la théorie de renormalisation des applications unimodales (l’approche herglotzien de H. Epstein), et la sommabilité de séries de Poincaré-Sundman dans le problème des 3 corps.

Abstract: In 1948 Hubert Wall introduced the particular class of analytic continued fractions called g-fractions. In the first part of this talk we describe briefly the definition and its principal properties. We show how g-fractions arise naturally in some problems related to dynamical systems theory and random walks. We introduce then the Ramanujan conjecture from the theory of limit periodic continued fractions and its solution given with help of g-fractions. The g-fractions can be effectively used in approximation theory. Here we explain how the anti-Herglotz functions approach of Henri Epstein can inspire us to use g-fractions in approximation of fixed points of renormalization operators in functional spaces. Finally, some applications of g-fractions to Sundman-Poincaré series from celestial mechanics are discussed.

Mathematical problems in Drosophila morphogenesis

A formal approach (mathematical models) describing the first two hours of development of the embryo of Drosophila (fruit fly) is presented. The first part of the talk is centered on the biological and biochemical events and processes that determine the form and shape (morphogenesis) of the embryo of Drosophila. Then we show the basic equations associated to some of the developmental processes and discuss the calibration and validation of the mathematical models with real experimental data. The models describe all the biochemical morphogenetic parameters measured in the Drosophila embryo with a relative error below 5% and account for the observed phenotypic plasticity and resilience. This approach leads to a precise mathematical definition of resilience, which we associate to the existence of a continuous family of Pareto optimal solutions of the models. Problems associated with conservation laws (symmetries) and optimization for ill posed problems and noisy objective functions will also be discussed.

Gravity as a Gauge Theory

I will explain how General Relativity in four space-time dimensions (with cosmological constant) can be reformulated as an SU(2) gauge theory of a certain type. The action is a (diffeomorphism invariant) functional of an SU(2) connection; no metric is present in the formulation of the theory. This formulation of GR is in many ways analogous to the one proposed many years ago by Eddington (Eddington’s Lagrangian is a function of just the affine connection and is given by the square root of the determinant of the Ricci tensor). The new formulation has some remarkable properties. First, on a 4-manifold, the space of SU(2) connections modulo gauge transformations has just 9 components per space-time point, as compared to 10 components of a metric tensor. Correspondingly, the action of the new formulation can be interpreted as a functional on the space of conformal classes of metrics. Thus, the conformal factor is not free to propagate in this formulation even off-shell. This has the effect that the action functional is (at least locally) convex – there is no conformal mode problem of the usual metric formulation of GR. Another remarkable property of the new formulation is that diffeomorphisms are very easy to deal with. The most natural gauge-fixing of these does not make the corresponding components of the connection propagate. As a result, in (linearized) quantum theory only 8 components of the connection propagate as compared to 10 metric components in the usual formulation. All these 8 components fit into a single irreducible representation of the Lorentz group, which makes the propagator very simple. There are also some remarkable simplifications in the structure of the interaction vertices. The full off-shell 3-vertex (in de Sitter space) contains just 3 terms as compared to a couple of dozen terms in the metric formulation. The 4-vertex is a couple of lines as compared to a couple of pages in the standard description. As an illustration of the formalism I will describe how the graviton scattering amplitudes are computed in this approach.

The new gauge-theoretic reformulation of GR also leads to (an infinite-parameter) family of modified gravitational theories, all propagating just two polarizations of the graviton, as GR. This leads to a rather strong claim that, in spite of the standard GR uniqueness theorems, General Relativity is not the only interacting theory of massless spin two particles. However, GR appears to be the only parity-invariant gravitational theory, as all the « deformations of GR » can be shown to be parity violating. I will also describe how matter is coupled in this approach, and give some speculations as to a possible UV completion of gravity.

On differential modules associated to de Rham representations in the imperfect residue field case

Let K be a CDVF of mixed characteristic (0,p) and G the absolute Galois group of K. When the residue field of K is perfect, Laurent Berger constructed a p-adic differential equation NdR(V) for any de Rham representation V of G. In this talk, we will generalize his construction when the residue field of K is not perfect. We also explain some ramification properties of our NdR , which are due to Adriano Marmora in the perfect residue field case.

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Diffeomorphometry in computational anatomy

Computational anatomy has emerged as a new subject focusing on the quantitative analysis of the variability of biological shapes with interesting challenges both from the mathematical and computational point of view. In this talk I will explain how a geometrical point of view based on the idea of shapes as structured spaces, actions of groups of diffeomorphisms and (sub)-Riemannian geometry provide nice vehicles to build a full processing framework called here diffeomorphometry.

A new spectral gap phenomenon in SL_2(R) and applications

From the tissue organization field theory of carcinogenesis to a theory of organisms

In 1999, C Sonnenschein and AM Soto proposed the tissue organization field theory (TOFT). The TOFT posits 1) that cancer is a tissue-based disease whereby carcinogens (directly) and germ-line mutations (indirectly) alter normal interactions between the stroma and adjacent epithelium; and 2) the default state of all cells is proliferation with variation and motility. This later premise is relevant to and compatible with evolutionary theory, and is diametrically opposed to that of the somatic mutation theory.

This theoretical change is incompatible with the reductionist genocentric perspective generated by the molecular biology revolution. Rather than forcing a “bricolage” we decided to frontally attack the problem by joining efforts with philosophers, mathematicians and theoretical biologists to search for principles upon which to build a theory of organisms .While the theory of evolution has provided an increasingly adequate explanation of phylogeny, biology still lacks a theory of organisms that would encompass ontogeny and life cycles, and thus phenomena on a conception to death time-scale.

To achieve this goal we propose that theoretical extensions of physics are required in order to grasp the living state of matter. Such extensions will help to describe the proper biological observables, i.e. the phenotypes. Biological entities must also follow the underlying principles used to understand inert matter. However, these physical laws and principles may not suffice to make the biological dynamics intelligible at the phenotypic level. By analogy with classical mechanics, where the principle of inertia is the default state of inert matter, we are proposing two aspects of the default state in biology, and a framing principle, namely: i) Default state: cell proliferation with variation as a constitutive property of the living. Variation is generated by the mere fact that cell division results in two overall similar, but not identical cells. ii) Default state: motility, which encompasses cell and organismic movements as well as movement within cells. iii) Framing principle: life phenomena exhibit never identical iterations of a morphogenetic process. Organisms are the consequence of the inherent variability generated by proliferation, motility and auto-organization which operate within the framing principle. From these basic premises, we will elaborate on the generation of robustness, the structure of theoretical determination, and the identification of biological proper observables.

An adapted coordinate system for light-signal-based cosmology

The "geodetic light-cone gauge" is a convenient coordinate system for the observation of light-like signals by a geodetic observer.
 
After introducing it I will give two examples on how it can be applied to physically interesting problems: i)  the precision determination of dark-energy parameters;  ii) the description of strong gravitational lensing. If time allows I will also mention some very recent work on gravitational bremsstrahlung from massless particle collisions.

Hybrid model of clot formation in flow and its applications to other phenomena

The process of blood coagulation and clot formation in vivo is not yet completely understood. One of the main questions related to haemostasis is why the clot stops growing in normal conditions before it completely obstructs the flow in the vessel, whereas, in pathologic cases, it can continue to grow, often with fatal consequences. Hence, revealing the mechanisms by which the clot grows and stops growing in the flow remains of great importance. In order to study this topic we have developed a hybrid DPD-PDE method where Dissipative Particle Dynamics (DPD) is used to model plasma flow and platelets, while the protein regulatory network is described by a system of partial differential equations. The model describes interactions between the platelet aggregation and the coagulation cascade. As a result of modelling we propose a new mechanism of clot growth and growth arrest in flow.

The developed model and its parts can be used as a base to modelling of different physiological phenomena related to cell-cell interactions and blood flows. In this context we discuss some prospects of this modelling approach (e.g. modelling of morphogenesis, atherosclerosis), as well as some ongoing modelling projects (e.g. cell deformation in a narrow flow, spontaneous blood coagulation).

Semi-direct product of categories and twisted actions of categorical groups

A (strict) categorical group is a (strict) monoidal category with an additional operation of 'inversion' under monoidal product. It has an equivalent description in terms of crossed modules. In order to study the representations/actions of categorical groups, we introduce a notion of semi-direct product of categories. It turns out that there are many interesting examples of semi-direct product of categories. In particular I will give some examples where one of the category is a (strict) categorical group. We use the notion of semi direct product of categories to define a kind of 'twisted action' of a categorical group. If time permits I will discuss a version of Schur's lemma in this context.
 

Reference:Twisted actions of categorical groups, S Chatterjee, A Lahiri, A Sengupta, Theory and Applications of Categories, Vol. 29, 2014, No. 8, pp 215-255

Entropy for sofic group actions

In 1958, Kolmogorov defined the entropy of a probability measure preserving transformation. Entropy has since been central to the classification theory of measurable dynamics. In the 70s and 80s researchers extended entropy theory to measure preserving actions of amenable groups (Kieffer, Ornstein-Weiss). My recent work generalizes the entropy concept to actions of sofic groups; a class of groups that contains for example, all subgroups of GL(n,C). Applications include the classification of Bernoulli shifts over a free group. This answers a question of Ornstein and Weiss.